24th Sep
2018

Intracytoplasmic Sperm Injection (ICSI)

Intracytoplasmic Sperm Injection is a procedure which is involved with IVF, i.e., in vitro fertilization by virtue of which a single sperm cell is injected directly into the cytoplasm of a mature egg cell that is held in place. This elaborate process is conducted in the lab by experienced embryologists using a holding tool and a fine glass injection needle. The only difference between Intracytoplasmic Sperm Injection with IVF is the method of introducing the sperm cell. ICSI is more advantageous as compared to the latter because it doesn’t require a large number of sperms in the surrounding media of the egg. Thus, it has provided hope to many males who might have a low sperm count. ICSI doesn’t depend on sperm count and the concept of “chance meeting” is also done away with.

Who is ICSI a Blessing For?

From the perspective of the patient, applying for an ICSI is similar to IVF.
Circumstances under which ICSI may be apt for are:

  • When sperm count is extremely low.
  • When sperm has no or little or even defective motility is abnormal by other means.
  • When sperms have been removed from the epididymis (MESA/PESA) or the testes.
  • When sperms have been removed from urine or by electro-ejaculation (TESE/TESA)
  • When there are large proportions of antibodies in semen.
  • When there has been a case of failure with traditional IVF procedure.

What Does ICSI Involve?

Stimulation of ovaries to encourage maturation of follicles thereby facilitating ovulation.

  • Retrieving the eggs safely.
  • Fertilizing the eggs with the sperm and culturing the embryo.
  • Transfer of embryo back into the uterus for further development.

What is the Success Rate for ICSI?

As such, the success rate of performing ICSI generally varies from individual to individual, particularly dependent on the age of the woman. According to statistics, about 25% of couples will be able to have a baby on the first attempt at ICSI.

Any Probable Risks of ICSI?

Although the success rate of an ICSI fertilization can be quite high, there are some probable risks that can’t be completely ignored. Unfortunately, not all fertilized zygotes using artificial techniques grow into healthy individuals.

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